
Desloratadine is a drug used to treat allergiesAllergyAllergy is a Disorder of the immune system often also referred to as atopy. Allergic reactions occur to Natural environmental substances known as allergens; these reactions are Acquired disorder, predictable and rapid. It is marketed under several trade names such as NeoClarityn, Claramax, Clarinex and Aerius. It is an active metaboliteMetaboliteMetabolites are the intermediates and products of metabolism. The term metabolite is usually restricted to small molecules. A primary metabolite is directly involved in normal growth, development, and reproduction of loratadine is a drug used to treat allergy, and marketed for its non-sedating properties. It is marketed by Schering-Plough and Shionogi in Japan under several trade names such as Claritin, Claritin-D, Claritine, Clarityn, Clarityne or Fristamin depending on the market; by Cadila as Lorfast; by Sandoz, which is also on the market.

This medication comes in many forms which are taken according to age group, severity of symptoms, and other factors. The regular Clarinex tablets relieve symptoms for up to 24 hours and are safe for ages 12 and up. Clarinex 24-hour combines the power of antihistamine and decongestant for people with seasonal rhinitis and congestion. Children as young as 6 months of age can receive relief from indoor allergies, while children 2 and over can experience relief from outdoor ones, with the bubblegum flavored Clarinex syrup.

DRUG CLASS AND MECHANISM: Desloratadine is an oral, long-acting antihistamine that is similar chemically to loratadine (Claritin). It is used to treat the symptoms caused by histamine. Histamine is a chemical that is responsible for many of the signs and symptoms of allergic reactions, for example, swelling of the lining of the nose, sneezing, and itchy eyes. Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cell to be "activated," releasing other chemicals which produce the effects that we associate with allergy.

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