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Use caution when driving, operating machinery, or performing other hazardous activities. Cyproheptadine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

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Take Periactin with or without food. You should drink an entire glass of water with your dose. You'll likely be directed to take each 4 mg tablet every 4 to 6 hours throughout the day.

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Symptoms of a cyproheptadine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

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