Report any side effects to your doctor you may have when taking Periactin. Side effects could include dizziness, dry mouth, headache, incontinence and fatigue. Drinking alcohol can worsen your side effects. If you have signs of an allergic reaction, such as swelling or difficulty breathing, seek out emergency care right away.
Periactin (CYPROHEPTADINE) is a piperidine antihistamine. Unlike other antihistamines, this drug also antagonizes serotonin receptors. This action makes Cyproheptadine useful in conditions such as vascular headache and anorexia. Cyproheptadine does not prevent the release of histamine but rather competes with free histamine for binding at HA-receptor sites. Cyproheptadine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. Most antihistamines possess significant anticholinergic properties, but Cyproheptadine exerts only weak anticholinergic actions. Blockade of central muscarinic receptors appears to account for Cyproheptadine's antiemetic effects, although the exact mechanism is unknown.
Report any side effects to your doctor you may have when taking Periactin. Side effects could include dizziness, dry mouth, headache, incontinence and fatigue. Drinking alcohol can worsen your side effects. If you have signs of an allergic reaction, such as swelling or difficulty breathing, seek out emergency care right away.
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